Kyle Stanton led ISU with a 3-for-4 performance, including one RBI and one run.
The Redbirds have now won two MVC titles in four seasons.
Illinois State improves to 17-4 at Duffy Bass Field.
Friday's win marked the ninth complete-game this season for ISU starters.
Redbird pitchers have eight complete-games this season.
WJBC Redbird Recap - Indiana State vs. ISU
Illinois State vs. Illinois held on March 27, 2012.
Personal: Born 8-2-93 in Orlando, Fla. ... son of Keith and Andrea ... has one brother, Matthew, and one sister, Emma ... major: Biochemistry (Pre-Medical)